发明名称 MODULAR CONSTRUCTION OF LIPOPHOSPHOLIPIDS
摘要 The present invention relates to fluorescent and/or targeting lipophilic compounds having the general formula (R1O)(R2O)P(O)-R3-R4-R5 wherein R1 and R2 are each independently a linear or branched, saturated or unsaturated C2-C24 alkyl, or a linear or branched, saturated or unsaturated C2-C24 monoalkenyl or polyalkenyl, the polyalkenyl having from 2 to 4 double bonds, or a linear or branched, saturated or unsaturated C2-C24 monoalkinyl or polyalkinyl, the polyalkinyl having from 2 to 4 triple bonds; R3 is selected from 0, S, -C(R6)2-, -CH(R7)-, -C(S)-N(R6)-, -CH(SR7)-S-S- or -N(R6)- wherein R6 is a hydrogen atom or a C1-C4 alkyl, and R7 is a C1-C4 alkyl; R4 comprises at least one junction function and at least one linker; and R5 is at least one chemical fluorescent group or at least one targeting group. Methods for preparing said lipophilic compounds are also disclosed.
申请公布号 US2013178609(A1) 申请公布日期 2013.07.11
申请号 US201113809379 申请日期 2011.07.11
申请人 HAELTERS JEAN-PIERRE;BERCHEL MATHIEU;COUTHON-GOURVES HELENE;JAFFRES PAUL-ALAIN;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS;UNIVERSITE DE BRETAGNE OCCIDENTALE 发明人 HAELTERS JEAN-PIERRE;BERCHEL MATHIEU;COUTHON-GOURVES HELENE;JAFFRES PAUL-ALAIN
分类号 C07F9/6558;C07H15/26 主分类号 C07F9/6558
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