发明名称 |
METHODS AND COMPOSITIONS FOR DETECTING THE ACTIVATION STATE OF MULTIPLE PROTEINS IN SINGLE CELLS |
摘要 |
The invention provides methods and compositions for simultaneously detecting the activation state of a plurality of proteins in single cells using flow cytometry. The invention further provides methods and compositions of screening for bioactive agents capable of coordinately modulating the activity of a plurality of proteins in single cells. The methods and compositions can be used to determine the protein activation profile of a cell for predicting or diagnosing a disease state, and for monitoring treatment of a disease state.
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申请公布号 |
US2013177970(A1) |
申请公布日期 |
2013.07.11 |
申请号 |
US201113094737 |
申请日期 |
2011.04.26 |
申请人 |
PEREZ OMAR D.;NOLAN GARRY P. |
发明人 |
PEREZ OMAR D.;NOLAN GARRY P. |
分类号 |
G01N33/53;C12Q1/00;C12Q1/02;C12Q1/37;C12Q1/48;G01N21/78;G01N33/50;G01N33/543;G01N33/569;G01N33/573;G01N33/58 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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