EX-VIVO METHOD FOR THE EARLY DIAGNOSIS OF MINIMAL HEPATIC ENCEPHALOPATHY BY MEANS OF THE DETERMINATION OF THE 3-NITROTYROSINE IN SERUM

摘要

An ex-vivo method for the early diagnosis of minimal hepatic encephalopathy by means of determining serum 3-nitrotyrosine relates to an ex-vivo method for the detection and early diagnosis of minimal hepatic encephalopathy (MHE) in patients with liver diseases, including cirrhosis, based on the presence of specific serum biomarkers, specifically by means of determining 3-nitrotyrosine (3-NT), which comprises obtaining serum or plasma obtained from the blood of patients and controls, and determining whether or not the measurement of the concentration of 3-nitrotyrosine obtained is greater than a specific level.