| 摘要 |
The present invention relates to a pharmaceutical composition including a miRNA486 expression inhibitor as an active ingredient for preventing and treating neurological disorders. More particularly, since it has been verified that interference with the expression of miR486 using an miR486 inhibitor overcomes the inhibition of NeuroD6, thereby inducing improvements in spinal cord injuries (SCI), the miR486 inhibitor can be used as an active ingredient in a pharmaceutical composition for preventing and treating neurological disorders, and further, the mechanism by which miR486 controls the expression of NeuroD6 can be applied in screening for candidate materials for preventing and treating neurological disorders. |
