| 摘要 |
<p>PURPOSE: A marker for early diagnosis of diabetic retinopathy (DR) is provided to early diagnose DR and to significantly predict or understand DR progression by measuring and comparing the expression level of a gene or a protein of which expression is reduced in a patient with DR. CONSTITUTION: A composition for diagnosis of DR contains an agent which measures mRNA or protein level of one or more genes selected from the group consisting of alpha-1-acid glycoprotein 2, alpha-1-antitrypsin, apolipoprotein A2, apolipoprotein A4, beta-2-glycoprotein 1, and gelsolin. A kit for diagnosing DR contains the composition. A method for providing information for diagnosing DR comprises the steps of: measuring the expression level of one or more genes or proteins selected from the group consisting of alpha-1-acid-glycoprotein 2, alpha-1-antitrypsin, apolipoprotein A2, apolipoprotein A4, beta-2-glycoprotein 1, and gelsolin in a biological sample; and comparing the expression level with the expression level of a control group sample.</p> |
