发明名称 |
Novel purinylpyridinylamino-2,4-difluorophenyl sulfonamide derivative, pharmaceutically acceptable salt thereof, preparation method thereof, and pharmaceutical composition with inhibitory activity against Raf kinase, containing same as active ingredient |
摘要 |
<p>The present invention relates to a novel purinylpyridinylamino-2,4-difluorophenyl sulfonamide derivative, a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutical composition with an inhibitory activity against Raf kinase, containing the same as an active ingredient. The purinylpyridinylamino-2,4-difluorophenyl sulfonamide derivative of the present invention effectively regulates the activity of B-raf kinase, and thus may be useful for preventing or treating cancer induced by the over-activation of Raf kinase, especially various melanoma, colorectal cancer, prostate cancer, thyroid cancer, ovarian cancer and the like.</p> |
申请公布号 |
AU2011337461(A1) |
申请公布日期 |
2013.07.11 |
申请号 |
AU20110337461 |
申请日期 |
2011.11.25 |
申请人 |
YOUAI CO., LTD |
发明人 |
SHIM, EUN KYONG;KIM, NAM DOO;SHIM, TAE BO;KIM, SEUNG YONG |
分类号 |
C07D401/04;A61K31/52;A61P35/00;C07D473/00 |
主分类号 |
C07D401/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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