发明名称 NANOPARTICLE ARIPIPRAZOLE FORMULATION
摘要 PROBLEM TO BE SOLVED: To provide compositions comprising nanoparticle aripiprazole, or salts thereof or derivatives thereof, having improved bioavailability, faster rates of absorption and a faster onset of therapeutic effect and to provide the methods.SOLUTION: The compositions of the stable nanoparticle aripiprazole, or salts thereof of derivatives thereof include: (a) aripiprazole particles whose average effective particle sizes of less than about 2,000 nm; (b) at least one kind of surface stabilizers. Dosage forms thereof are also provided.
申请公布号 JP2013136621(A) 申请公布日期 2013.07.11
申请号 JP20130042916 申请日期 2013.03.05
申请人 ELAN PHARMA INTERNATL LTD 发明人 JENKINS SCOTT;MERISKO-LIVERSIDE ELAINE
分类号 A61K31/496;A61K9/06;A61K9/107;A61K9/12;A61K9/14;A61K9/19;A61K9/20;A61K9/22;A61K9/48;A61K9/52;A61K31/5415;A61K31/551;A61K31/5513;A61K31/554;A61K45/00;A61K47/02;A61K47/04;A61K47/10;A61K47/12;A61K47/14;A61K47/18;A61K47/20;A61K47/22;A61K47/24;A61K47/26;A61K47/28;A61K47/32;A61K47/34;A61K47/36;A61K47/38;A61K47/42;A61K47/44;A61P25/00;A61P25/14;A61P25/16;A61P25/18;A61P25/24 主分类号 A61K31/496
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