发明名称 |
DEVICE AND METHOD FOR CORNEAL DELIVERY OF RIBOFLAVIN BY IONTOPHORESIS FOR THE TREATMENT OF KERATOCONUS |
摘要 |
Ocular iontophoresis device and method for delivering any ionized drug solution to the cornea includes: a reservoir containing a solution suitable to be positioned on the eye; an active electrode disposed in or on the reservoir; and a passive electrode suitable to be placed on the skin of the subject, elsewhere on the body; elements for irradiating the cornea surface with suitable light for obtaining corneal cross-linking after the drug delivery; wherein the reservoir and the active electrode are transparent to UV light and/or visible light and/or IR light. The method includes: positioning the iontophoretic device on the eye to be treated; driving the solution by a cathodic current applied for 0.5 to 5 min, at an intensity not higher than 2 mA; and thereafter irradiating, with UV light for 5 to 30 min at a power of 3 to 30 mW/cm2; thereby obtaining the corneal cross-linking of the solution.
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申请公布号 |
US2013178821(A1) |
申请公布日期 |
2013.07.11 |
申请号 |
US201113824850 |
申请日期 |
2011.01.12 |
申请人 |
FOSCHINI FULVIO;ROY PIERRE;STAGNI EDOARDO;CAVALLO GIOVANNI;LUCIANI GIULIO;SOOFT ITALIA SPA |
发明人 |
FOSCHINI FULVIO;ROY PIERRE;STAGNI EDOARDO;CAVALLO GIOVANNI;LUCIANI GIULIO |
分类号 |
A61F9/00;A61N1/30;A61N5/06 |
主分类号 |
A61F9/00 |
代理机构 |
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主权项 |
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