发明名称 |
POTENTIATOR OF ACTIVITY OF ANTI-CANCER AGENT AND USE THEREOF, AND BIOMARKER FOR PREDICTION OF PROGNOSIS IN CANCER PATIENT AND USE THEREOF |
摘要 |
Disclosed is a means for improving the clinical outcomes of cancer therapy. Specifically disclosed is an activity potentiator comprising a compound capable of inhibiting the expression of RFP (RET finger protein) gene or the activity of RFP as an active ingredient. The activity of an anti-cancer agent having an oxidative stress inducing ability can be potentiated by using the anti-cancer agent in combination with the activity potentiator. Further specifically disclosed are a biomarker useful for the recognition of prognosis in a cancer patient and use of the biomarker. |
申请公布号 |
US2013177660(A1) |
申请公布日期 |
2013.07.11 |
申请号 |
US201213728048 |
申请日期 |
2012.12.27 |
申请人 |
NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY;NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY |
发明人 |
TAKAHASHI MASAHIDE;KATO TAKUYA;KIKKAWA FUMITAKA |
分类号 |
C12N15/113;A61K31/713;A61K33/24;C07K14/435;C07K16/18;G01N33/68 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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