发明名称 Prevention of adverse effects caused by EpCAMxCD3 bispecific antibodies
摘要 The present invention relates to a glucocorticoid (GC) for use in the amelioration, treatment and/or prophylaxis of hepatic and/or gastroenterological adverse events caused by an EpCAMxCD3 bispecific antibody, wherein the administration of the GC is started prior to the administration of the EpCAMxCD3 bispecific antibody. Kits comprising a GC, an EpCAMxCD3 bispecific antibody and instructions for use indicating that the GC is to be employed for the treatment, amelioration and/or prophylaxis of hepatic and/or gastroenterological adverse events caused by said EpCAMxCD3 bispecific antibody in a patient, are also disclosed.
申请公布号 AU2012350429(A1) 申请公布日期 2013.07.11
申请号 AU20120350429 申请日期 2012.12.07
申请人 AMGEN RESEARCH (MUNICH) GMBH 发明人 STIENEN, SABINE
分类号 A61K31/573;A61K39/395 主分类号 A61K31/573
代理机构 代理人
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