| 发明名称 |
CULTURE METHOD FOR MAINTENANCE AND PROPAGATION OF STEM CELLS BY LYSOPHOSPHOLIPID SIGNAL CONTROL |
| 摘要 |
<p>The problem addressed by the present invention is to provide a simple culture method for improving the number of times stem cells divide during ex vivo stem cell culture while maintaining the function of the stem cells. A method for culturing stem cells that comprises a step for culture of stem cells under conditions by which the function of the lysophosphatidic acid (LPA) receptor is inhibited is provided as a means for solving the problem.</p> |
| 申请公布号 |
WO2013103089(A1) |
申请公布日期 |
2013.07.11 |
| 申请号 |
WO2012JP82979 |
申请日期 |
2012.12.19 |
| 申请人 |
TOHOKU UNIVERSITY |
发明人 |
KIKUCHI, TOSHIAKI;KANEHIRA, MASAHIKO;NUKIWA, TOSHIHIRO |
| 分类号 |
C12N5/0775;A61K8/49;A61K8/55;A61K31/42;A61K31/662;A61K31/675;A61K45/00;A61P17/00;A61P17/02;A61P43/00;A61Q19/08;C12N15/09 |
主分类号 |
C12N5/0775 |
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