发明名称 |
NUCLEIC ACID FRAGMENTS FROM A RIBOSOMAL PROTEIN PROMOTER FOR ENHANCING GENE EXPRESSION |
摘要 |
The present invention relates to nucleic acid fragments and constructs comprising genomic nucleotide sequences from the promoter region of a 60S ribosomal protein L32 gene (RPL32), for the production of a gene product of interest in a eukaryotic, preferably mammalian, host cell in the presence of a stringent selectable marker. The invention further relates to host cells comprising the nucleic acid constructs, to methods for generating the host cells and to methods for producing a gene product of interest using the host cells. |
申请公布号 |
EP2611915(A1) |
申请公布日期 |
2013.07.10 |
申请号 |
EP20110751675 |
申请日期 |
2011.08.31 |
申请人 |
CELLAGENICS B.V. |
发明人 |
OTTE, ARIE PIETER;HOEKSEMA, FEMKE;VERHEES, JOHN ANTONIUS;VAN BLOKLAND, HENRICUS JOHANNES MARIA |
分类号 |
C12N15/10;C12N15/85 |
主分类号 |
C12N15/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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