发明名称 PROCESS FOR THE PREPARATION OF PLEUROMUTILINS
摘要 A process for the preparation of a compound of formula in the form of a single stereoisomer, comprising deprotecting the amine group in an N-protected amino-hydroxy-cyclohexylsulfanyl-acetyl-mutilin of formula wherein R is an amine protecting group in the form of a single stereoisomer, and isolating a compound of formula I in the form of a single stereoisomer obtained from the reaction mixture; compounds obtainable by such processes, e.g. a compound of formula I in a crystalline form, or salts of a compound of formula I in crystalline form, and processes for the preparation of intermediates for the production of a compound of formula I.
申请公布号 KR20130079406(A) 申请公布日期 2013.07.10
申请号 KR20127030731 申请日期 2011.05.23
申请人 NABRIVA THERAPEUTICS AG 发明人 RIEDL ROSEMARIE;HEILMAYER WERNER;SPENCE LEE
分类号 C07C315/06;A61K31/215;A61P17/00;C07C323/52 主分类号 C07C315/06
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