发明名称 3-(1H-INDOL-3-YL)-4-[2-(4-METHYLPIPERAZIN-1-YL)QUINAZOLIN-4-YL]PYRROLE-2,5-DIONE SALTS
摘要 FIELD: chemistry.SUBSTANCE: invention relates to 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione salts in crystalline form, where said salts are formed with an acid selected from hydrochloric acid, maleic acid, malonic acid and methanesulphonic acid. The invention also relates to a method of producing said salts, a pharmaceutical composition containing said salts and a method of treating diseases or disorders mediated by T lymphocytes and/or PKC, which involves addition of said salts.EFFECT: high stability.10 cl, 2 ex
申请公布号 RU2487128(C2) 申请公布日期 2013.07.10
申请号 RU20090136670 申请日期 2008.03.06
申请人 NOVARTIS AG 发明人 KARPINSKI P'OTR;PAPOUTSAKIS DIMITRIS;JOUEHLL GAJ
分类号 C07D403/14;A61K31/517;A61P37/00 主分类号 C07D403/14
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