发明名称 |
DRUG DELIVERY SYSTEM FOR CONTROLLED RELEASE OF HUMAN GROWTH HORMONE FUSED WITH HUMAN ANTIBODY FC BY USING POLYMER MEMEBRANE |
摘要 |
PURPOSE: A nanoporous membrane with nanopores, which is a depot system capable of controlling the release of functional proteins in cosmetics is provided to be used as a nanoporous carrier based on a block copolymer. CONSTITUTION: A nanoporous membrane is prepared using PS-b-PMMA[polystyrene-block-poly (methyl methacrylate) polymers. The particle size of nanopores of the nanoporous membrane is 10-20 nm. The average of the particle size is 15 nm. A method for delivering antibody-based proteins constantly maintains release rate using the nanoporous membrane. The nanoporous membrane is used in a sustained release drug delivery system of the antibody-based proteins.
|
申请公布号 |
KR20130079011(A) |
申请公布日期 |
2013.07.10 |
申请号 |
KR20120000243 |
申请日期 |
2012.01.02 |
申请人 |
POSTECH ACADEMY-INDUSTRY FOUNDATION |
发明人 |
KIM, EUNG SAM;JANG, DO SOO;YANG, SEUNG YUN;CHOI, KWAN YONG;SUNG, YOUNG CHUL;KIM, JIN KON |
分类号 |
A61K9/22;A61K9/16;A61K39/395;A61K47/48 |
主分类号 |
A61K9/22 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|