摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to steroid ligands for use in nuclear receptor-based inducible gene expression systems. The invention also relates to methods of modulating the expression of genes of interest using a system containing one or more nuclear receptor complexes and one or more steroid ligands. Other aspects include ligand compositions including therapeutic compositions.EFFECT: improved method.21 cl, 1 ex, 9 tbl, 20 dwg |