ANTIBACTERIAL COMPOSITION CONTAINING IXERIS POLYCEPHALA CASSINI EXTRACT AND ACTIVE INGREDIENT ISOLATED FROM THE SAME

摘要

PURPOSE: An Ixeris polycephala Cassini extract, and urs-12-ene and olean-12-en-3-ol isolated from the extract are provided to ensure excellent antibacterial activity against gram-negative bacteria, gram-positive bacteria, or helicobacter pylori, and to be used as an antibacterial composition and a therapeutic agent for treating disease caused by bacteria. CONSTITUTION: An antibacterial pharmaceutical composition contains an Ixeris polycephala Cassini extract as an active ingredient. The extract is prepared using water, C1-C4 alcohols, or a mixture thereof. The extract has antibacterial activity against one or more microbes selected from the group consisting of helicobacter pylori, Staphylococcus aureus, and E.coli. The antibacterial pharmaceutical composition contains one or more compounds selected from the group consisting of chemical formulas 1 and 2, as active ingredients. The compounds are isolated from the extract.