发明名称 Antibacterial compositions
摘要 Compounds of formula (I) have antibacterial activity: wherein: m is 0 or 1; Q is hydrogen or cyclopropyl; Alk is an optionally substituted, divalent C1-C6 alkylene, alkenylene or alkynylene radical which may contain an ether (-O-), thioether (-S-) or amino (-NR)- link, wherein R is hydrogen, -CN or C1-C3 alkyl; X is -C(=O)NR6-, -S(O)NR6-, -C(=O)O- or -S(=O)O- wherein R6 is hydrogen, optionally substituted C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, -Cyc, or -(C1-C3 alkyl)-Cyc wherein Cyc is optionally substituted monocyclic carbocyclic or heterocyclic having 3-7 ring atoms; Z is N; R2 and R3 are as defined in the description.
申请公布号 US8481544(B2) 申请公布日期 2013.07.09
申请号 US201113154485 申请日期 2011.06.07
申请人 HAYDON DAVID JOHN;CZAPLEWSKI LLOYD GEORGE;PALMER NICHOLAS JOHN;MITCHELL DALE ROBERT;ATHERALL JOHN FREDERICK;STEELE CHRISTOPHER RICHARD;LADDUWAHETTY TAMARA;BIOTA EUROPE LIMITED 发明人 HAYDON DAVID JOHN;CZAPLEWSKI LLOYD GEORGE;PALMER NICHOLAS JOHN;MITCHELL DALE ROBERT;ATHERALL JOHN FREDERICK;STEELE CHRISTOPHER RICHARD;LADDUWAHETTY TAMARA
分类号 A61K31/497;A61K31/4365;C07D241/12;C07D513/04 主分类号 A61K31/497
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