发明名称 |
Nucleic acid molecules encoding anti-P-selectin antibodies |
摘要 |
This invention relates to anti-P-selectin antibodies and, in particular, to anti-P-selectin antibodies and variants thereof that contain an Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suffering from critical limb ischemia or peripheral arterial occlusive disease (CLI/PAOD).
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申请公布号 |
USRE44359(E1) |
申请公布日期 |
2013.07.09 |
申请号 |
US201213471899 |
申请日期 |
2012.05.15 |
申请人 |
GRAUS YVO;HIMBER JACQUES;JANSEN-MOLENAAR MIRANDA;KLING DOROTHEE;KOPETZKI ERHARD;PARREN PAUL;REBERS FRANK;STEINER BEAT;STERN ANNE;BRAEMER PAMELA;STUBENRAUCH KAY-GUNNAR;VAN DE WINKEL JAN;VAN VUGT MARTINE;HOFFMANN-LA ROCHE INC |
发明人 |
GRAUS YVO;HIMBER JACQUES;JANSEN-MOLENAAR MIRANDA;KLING DOROTHEE;KOPETZKI ERHARD;PARREN PAUL;REBERS FRANK;STEINER BEAT;STERN ANNE;BRAEMER PAMELA;STUBENRAUCH KAY-GUNNAR;VAN DE WINKEL JAN;VAN VUGT MARTINE |
分类号 |
C12N15/13;A61K39/395;C07K16/28;C07K16/46;C12N5/10;C12N15/12;C12N15/63 |
主分类号 |
C12N15/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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