发明名称 |
Method of synthesis of Bosentan, its polymorphic forms and its salts |
摘要 |
The present invention relates to alkaline earth metal salts of bosentan, anyhdrous bosentan, polymorphic forms thereof, amorphous bosentan and processes for preparing them. The present invention further relates to a process for the preparation of bosentan and its pharmaceutically acceptable salts.
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申请公布号 |
US8481730(B2) |
申请公布日期 |
2013.07.09 |
申请号 |
US20090811279 |
申请日期 |
2009.01.02 |
申请人 |
RAO DHARMARAJ RAMACHANDRA;KANKAN RAJENDRA NARAYANRAO;PHULL MANJINDER SINGH;SAWANT ASHWINI AMOL;CIPLA LIMITED |
发明人 |
RAO DHARMARAJ RAMACHANDRA;KANKAN RAJENDRA NARAYANRAO;PHULL MANJINDER SINGH;SAWANT ASHWINI AMOL |
分类号 |
C07D403/04;A61K31/506;A61P9/12;C07D239/69 |
主分类号 |
C07D403/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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