发明名称 |
Stabilization of liquid solutions of recombinant protein for frozen storage |
摘要 |
The invention relates to a method for stabilizing a bulk solution of recombinant protein for frozen storage, which comprises providing a partially-purified solution of recombinant protein which has a monovalent salt concentration of at least 100 mM, and adding a carbohydrate to said solution in an amount sufficient that, upon freezing, the solution has a glass transition temperature of -56 °C or higher. |
申请公布号 |
AU2008245821(B2) |
申请公布日期 |
2013.07.04 |
申请号 |
AU20080245821 |
申请日期 |
2008.04.22 |
申请人 |
BAYER HEALTHCARE LLC |
发明人 |
JOSHI, OMKAR;WANG, DEQIAN;DESPONDS, ARNAUD;WU, PAUL;TSVETKOVA, NELLY |
分类号 |
A61K38/00 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|