| 摘要 |
PROBLEM TO BE SOLVED: To provide improved systems for biological production of carotenoids.SOLUTION: The invention provides oleaginous fungi (including, for example, yeast or other unicellular fungi) that produce one or more carotenoids. The invention also provides methods for constructing such yeast and fungi, methods for using such yeast and fungi to produce carotenoids, and methods for preparing carotenoid-containing compositions, such as food or feed additives, or nutritional supplements, using carotenoids produced in such oleaginous yeast or fungi. In particular, the invention provides systems and methods for generating yeast and fungi containing one or more oleaginic and/or carotenogenic modifications that increase the oleaginicity and/or alter their carotenoid-producing capabilities as compared with otherwise identical organisms that lack the modification(s). |
