发明名称 Phenolic hydrazone macrophage migration inhibitory factor inhibitors
摘要 Provided are various compounds of Formula (I): Also provided are pharmaceutical compositions comprising the above compounds. Additionally, methods of inhibiting macrophage migration inhibitory factor (MIF) activity in a mammal are provided, as are methods of treating or preventing inflammation in a mammal. Further provided are methods of treating a mammal having sepsis, septicemia, and/or endotoxic shock. Also provided are methods of treating a mammal having an autoimmune disease, and methods of treating a mammal having a tumor.
申请公布号 AU2007231012(B2) 申请公布日期 2013.07.04
申请号 AU20070231012 申请日期 2007.03.23
申请人 THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH 发明人 AL-ABED, YOUSEF
分类号 C07D487/00;A01N37/18 主分类号 C07D487/00
代理机构 代理人
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