Provided are methods and compositions for the production of novel antibodies that bind specifically to a target antigen. These methods and compositions are particularly useful for producing antibodies having the antigen binding specificity of a reference antibody but with improved properties (e.g., binding affinity, immunogenicity, and thermodynamic stability) relative to the reference antibody.
申请公布号
WO2012125733(A3)
申请公布日期
2013.07.04
申请号
WO2012US29086
申请日期
2012.03.14
申请人
X-BODY, INC.;CHEN, YAN;WOOLF, TOD, M.;WAGNER, RICHARD, W.