| 发明名称 |
Use of chimeric antigen receptor-modified T cells to treat cancer |
| 摘要 |
The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain. |
| 申请公布号 |
AU2011338200(A1) |
申请公布日期 |
2013.07.04 |
| 申请号 |
AU20110338200 |
申请日期 |
2011.12.09 |
| 申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
JUNE, CARL H.;LEVINE, BRUCE L.;PORTER, DAVID L.;KALOS, MICHAEL D.;MILONE, MICHAEL C. |
| 分类号 |
A61K39/00;C07H21/04 |
主分类号 |
A61K39/00 |
| 代理机构 |
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| 主权项 |
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