发明名称 METHOD OF ACTIVATION OF OXAZAPHOSPHORINES
摘要 The present invention provides a method of hydroxylating or oxidizing a compound of interest in a subject (e.g., a cytotoxic oxazaphosphorine prodrug), by administering the compound of interest to the subject; and concurrently administering the subject a metalloporphyrin in an amount effective to hydroxylate or oxidize the compound of interest in the subject.
申请公布号 US2013172296(A1) 申请公布日期 2013.07.04
申请号 US201313763085 申请日期 2013.02.08
申请人 DUKE UNIVERSITY 发明人 SPASOJEVIC IVAN;COLVIN MICHAEL O.;BATINIC-HABERLE INES;LUDEMAN SUSAN M.;GAMCSIK MICHAEL P.
分类号 A61K31/675;A61K31/555 主分类号 A61K31/675
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