发明名称 STEROLS DERIVATIVE, AND PREPARATION METHOD AND PURPOSE THEREOF
摘要 The present invention relates to the field of pharmaceutical chemicals, and provides a sterols derivative, and a preparation method and purpose thereof. Specifically, the present invention relates to a compound shown in formula I, or pharmaceutically acceptable salts thereof, wherein R1 is selected from -OH, =O, H, and alkyl group containing one to three carbon atoms; R2 is selected from -OH, H, and alkyl group containing one to three carbon atoms; R3 is selected from -OH, =O, H, and alkyl group containing one to three carbon atoms; R4 is selected from -OH, H, and alkyl group containing one to three carbon atoms; and any 0, 1, 2, 3, or 4 of R1, R2, R3 and R4 is -OH. The compound of the present invention can effectively suppress HMG-CoA reductase, tumor cells, and lipase, and has the potential of being used as tumor-reducing or anti-tumor medicine or diet pills.
申请公布号 WO2013097681(A1) 申请公布日期 2013.07.04
申请号 WO2012CN87360 申请日期 2012.12.25
申请人 BEIJING PEKING UNIVERSITY WBL BIOTECH CO., LTD. 发明人 DUAN, ZHENWEN;GUO, SHUREN;LI, XUEMEI
分类号 C07J71/00;A61K31/58;A61K36/06;A61P3/06;A61P9/10;A61P35/00 主分类号 C07J71/00
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