| 发明名称 |
EPITHELIAL MEMBRANE PROTEIN 2 (EMP2) BINDING REAGENTS AND THEIR THERAPEUTIC USES IN OCULAR DISEASES |
| 摘要 |
A method is disclosed for treating diseases or disorders of the eye involving undesired expression of vascular endothelial growth factor (VEGF) by administration of endothelial membrane protein 2 (EMP2) inhibitor. The present invention relates to the direct treatment of macular degeneration, particularly age-related macular degeneration (AMD), by administering an EMP2 inhibitor intraocularly or systemically. |
| 申请公布号 |
EP2536433(A4) |
申请公布日期 |
2013.07.03 |
| 申请号 |
EP20110745457 |
申请日期 |
2011.02.22 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;UNITED STATES GOVERNMENT DEPARTMENT OF VETERANS AFFAIRS |
发明人 |
GORDON, LYNN K.;BRAUN, JONATHAN;MORALES, SHAWN;TELANDER, DAVID, G.;WADEHRA, MADHURI |
| 分类号 |
C07K16/28;A61K31/7105;A61K38/16;A61K39/395;A61P27/00;A61P27/02;C12N15/113 |
主分类号 |
C07K16/28 |
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