发明名称 |
LABELING AGENT AND AMINO ACID SEQUENCE USING SAME, AND METHOD FOR PERFORMING SIMULTANEOUS QUANTITATIVE ANALYSIS OF MULTIPLE PROTEINS |
摘要 |
<p>The present invent ion provides a compound that can utilize hydrogen isotope and, at the same time, can quantify multiplexed samples at one time, as well as decreasing the cost for synthesis of the labeling agent. In addition, the present invention provides a novel method for quantitatively analyzing protein and peptide analytes having different quantities form each other using the labeling agent, wherein y-type fragment ions having a high mass which comprises the analyte remained after coupling the labeling agent with the analyte and then removing a part of the labeling agent through tandem mass spectrometry are utilized to conduct the quantitative analysis.</p> |
申请公布号 |
EP2610243(A2) |
申请公布日期 |
2013.07.03 |
申请号 |
EP20110820170 |
申请日期 |
2011.08.23 |
申请人 |
POSTECH ACADEMY-INDUSTRY FOUNDATION |
发明人 |
SHIN, SEUNG KOO;YOON, HYE JOO;JUNG, YONG SIK;LEE, HEE YOON;SUH, MIN SOO;SEO, JONG CHEOL |
分类号 |
C07C233/47;G01N33/58;G01N33/68 |
主分类号 |
C07C233/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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