摘要 |
An immunogenic composition comprising, as effective ingredients: an immunogenic microparticle composed of an antigen-adjuvant microparticle complex wherein an antigen(s) is/are encapsulated in an adjuvant microparticle composed of an amphiphilic polymer(s) whose hydrophobic segment(s) is/are poly(hydroxy acid); and a surfactant; the surfactant being encapsulated in the immunogenic microparticle, has a high immune-activating capacity in a living body even with a small antigen amount and/or a small number of doses. |