1H-Benzo[d]imidazol-5-yl compounds and composition for treating inflammatory diseases

摘要

Provided are heterocyclic compounds, having effects of treating and preventing inflammatory diseases and treating skin wounds, and particularly, exhibiting effects of recovering disrupted skin barriers, mitigating inflammation, and pruritus. Also, a composition containing the compound as an effective component can be used to mitigate vairous inflammatory diseases and protease activated receptor-2 (PAR-2)-overexpressed diseases, and can be particulalry used as a composition having an anti-inflmammatory function in inflammatory skin diseases including atopic dermatitis and the like, by inhibiting PAR-2 activity.