| 发明名称 |
IN VITRO RECONSTITUTION OF SEGMENTED NEGATIVE-STRAND RNA VIRUSES |
| 摘要 |
There is disclosed a method for generating in cultured cells infectious viral particles of a segmented negative-strand virus by an entirely vector-based system without the aid of a helper virus. The method may, for example, be particularly useful for producing modified influenza viruses.
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| 申请公布号 |
CA2379012(C) |
申请公布日期 |
2013.07.02 |
| 申请号 |
CA20002379012 |
申请日期 |
2000.07.14 |
| 申请人 |
MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY |
发明人 |
BROWNLEE, GEORGE GOW;FODOR, ERVIN;PALESE, PETER;GARCIA-SASTRE, ADOLFO |
| 分类号 |
C12N15/09;C12N15/86;A61K35/76;A61K39/12;A61K39/145;A61P31/14;A61P31/16;C12N5/10;C12N7/00;C12N7/01;C12N7/02;C12N7/04;C12R1/93 |
主分类号 |
C12N15/09 |
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