| 摘要 |
Substituted indole derivatives of formula (I) wherein the radicals have e. g. the following meaning: R1 is hydrogen, -C1-6-alkyl, R2 is hydrogen, -C1-6-alkyl or cycloC3-12-alkyl; R3 is OR R4 is hydrogen or halogen, R5 is hydrogen, -C1-6-alkyl R6 is hydrogen, -C1-6-alkyl R is hydrogen or -C1-6-alkyl; X is a group -C(O)CH2- or -CH=CH-; R7 is hydrogen are potent inhibitors of Abeta peptide polymerization and can be used for the treatment of e.g. Alzheimers disease or ocular disorders. |
