摘要 |
The present invention relates to a process for the preparation of polymer conjugates of i.pi.dolocarbazole compounds, in particular of polymer conjugates of K-252a and derivatives thereof, by a synthetic route which results in a highly pure product, with a high product yield. In a further aspect the present invention relates to novel polymer conjugates of K-252a and derivatives thereof, wherein the chemical group linking the polymer unity to the K-252a or to the K-252a derivative compound is characterised by a 5-member oxazolidindionic cyclic structure. These novel polymer conjugates are obtained through the novel synthetic route with high purity and high yields, |
申请人 |
CREABILIS S.A. |
发明人 |
BAGNOD, RAFFAELLA;BECCARIA, LUCA;BERTARIONE RAVA ROSSA, LUISA;CRISCUOLO, DOMENICO;LORENZETTO, CHIARA;MAINERO, VALENTINA;MARCONI, ALESSANDRA;PINCELLI, CARLO;TRAVERSA, SILVIO |