| 发明名称 |
alpha-ketoamide derivatives useful endothelial lipase inhibitors |
| 摘要 |
The present invention is directed to alpha-ketoamide derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by endothelial lipase, for example, cardiovascular disorders.
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| 申请公布号 |
US8476302(B2) |
申请公布日期 |
2013.07.02 |
| 申请号 |
US201113245137 |
申请日期 |
2011.09.26 |
| 申请人 |
GRECO MICHAEL N.;CONNELLY MARGERY A.;GHOSH SHYAMALI;HLASTA DENNIS J.;LAWSON EDWARD C.;STROBEL ERIC;WEIDNER-WELLS MICHELE A.;YE HONG;JANSSEN PHARMACEUTICA N.V. |
发明人 |
GRECO MICHAEL N.;CONNELLY MARGERY A.;GHOSH SHYAMALI;HLASTA DENNIS J.;LAWSON EDWARD C.;STROBEL ERIC;WEIDNER-WELLS MICHELE A.;YE HONG |
| 分类号 |
A61K31/4245;A61K31/433;A61K31/4439;C07D271/107;C07D285/12;C07D417/12 |
主分类号 |
A61K31/4245 |
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