发明名称 |
Long-acting coagulation factors and methods of producing same |
摘要 |
Polypeptides and polynucleotides encoding same comprising at least one carboxy-terminal peptide (CTP) of chorionic gonadotrophin attached to a carboxy terminus of a coagulation factor and not to an amino terminus are disclosed. Pharmaceutical compositions comprising the polypeptides and polynucleotides of the invention and methods of using same are also disclosed.
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申请公布号 |
US8476234(B2) |
申请公布日期 |
2013.07.02 |
申请号 |
US20100826754 |
申请日期 |
2010.06.30 |
申请人 |
FIMA UDI EYAL;HART GILI;PROLOR BIOTECH INC. |
发明人 |
FIMA UDI EYAL;HART GILI |
分类号 |
A61K38/36;A61K38/24;C07K14/59;C07K14/745 |
主分类号 |
A61K38/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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