| 摘要 |
Novel compounds of the structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK- activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.
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| 申请人 |
MERCK SHARP & DOHME CORP.;METABASIS THERAPEUTICS, INC. |
发明人 |
BOOKSER, BRETT C.;DANG, QUN;GIBSON, TONY S.;JIANG, HONGJIAN;CHUNG, DE MICHAEL;BAO, JIANMING;JIANG, JINLONG;KASSICK, ANDY;KEKEC, AHMET;LAN, PING;LU, HUAGANG;MAKARA, GERGELY M.;ROMERO, F. ANTHONY;SEBHAT, IYASSU;WILSON, DAVID;WODKA, DARIUSZ |
