发明名称 |
Meganuclease recombination system |
摘要 |
The invention relates to a set of genetic constructs which allow the efficient and reproducible introduction of a specific nucleotide sequence at a fixed position in the genome by generating a double strand break at a specific position in the genome using a meganuclease and so stimulating a homologous recombination event at this locus between the genomic site and a transfected donor sequence. The present invention also relates to methods using these constructs and to these materials in the form of a kit.
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申请公布号 |
US8476072(B2) |
申请公布日期 |
2013.07.02 |
申请号 |
US200913125193 |
申请日期 |
2009.10.23 |
申请人 |
CABANIOLS JEAN-PIERRE;CHOULIKA ANDRE;DELENDA CHRISTOPHE;CELLECTIS |
发明人 |
CABANIOLS JEAN-PIERRE;CHOULIKA ANDRE;DELENDA CHRISTOPHE |
分类号 |
C12N15/87;C12N15/00;C12N15/10 |
主分类号 |
C12N15/87 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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