发明名称 |
Tubulysin D analogues |
摘要 |
The present invention provides novel tubulysin analogues, methods of making and methods of using such analogues and conjugates thereof. The compounds of the invention are highly potent cell-growth inhibitors have been developed that are smaller and considerably more stable than tubulysin D.
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申请公布号 |
US8476451(B2) |
申请公布日期 |
2013.07.02 |
申请号 |
US20080669364 |
申请日期 |
2008.07.21 |
申请人 |
ELLMAN JONATHAN A.;PATTERSON ANDREW W.;PELTIER HILLARY;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
ELLMAN JONATHAN A.;PATTERSON ANDREW W.;PELTIER HILLARY |
分类号 |
A61K31/426;A01N43/78;A61K31/427;C07D277/30 |
主分类号 |
A61K31/426 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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