6-AMINOPYRIDIN-3-OL DERIVATIVE OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING ANGIOGENESIS-RELATED DISEASE COMPRISING THE SAME

摘要

PURPOSE: A 6-aminopyridine-3-ol derivative or a pharmaceutically acceptable salt thereof is provided to suppress angiogenesis in a chorio-allantoic membrane model, and to be used as a drug for preventing or treating diseases caused by angiogenesis. CONSTITUTION: A 6-aminopyridine-3-ol derivative of chemical formula 1 or a pharmaceutically acceptable salt thereof is provided. The pharmaceutically acceptable salt is an organic acid selected from the group consisting of oxalic acid, maleic acid, fumaric acid, malic acid, tartaric acid, citric acid, and benzoic acid, or an inorganic acid selected from the group consisting of hydrochloric acid, sulfuric acid, phosphoric acid, and hydrobromic acid. A pharmaceutical composition for preventing or treating diseases caused by angiogenesis contains the derivative of chemical formula 1 or a pharmaceutically acceptable salt thereof as an active ingredient.