摘要 |
Disclosed is the use of a population of metallic nanoparticles to prepare a pharmaceutical composition intended to perturb, alter or destroy target mammalian cells, selected in the group consisting of benign cells, pre-malignant cells and malignant cells, when said cells are exposed to ionizing radiations, wherein the nanoparticles are made of a metal having an atomic number (Z) of at least 25 and the mean largest size of the nanoparticles of the population is between about 80 and 105 nm, and wherein the metallic nanoparticle is covered with a biocompatible coating. |