发明名称 |
Adamantyl derivatives as inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme |
摘要 |
<p>ADAMANTYL DERIVATIVES AS INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 Abstract The present invention relates to compounds which are inhibitors of the 11 -beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of I 1-beta-hydroxysteroid dehydrogenase Type I enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action. (5788716_I):KZA</p> |
申请公布号 |
AU2011253958(B2) |
申请公布日期 |
2013.06.27 |
申请号 |
AU20110253958 |
申请日期 |
2011.12.12 |
申请人 |
ABBVIE INC. |
发明人 |
SORENSEN, BRYAN K.;YONG, HONG;LINK, JAMES T.;ROHDE, JEFFREY J.;YEH, VINCE S.;PATEL, JYOTI R.;WINN, MARTIN;SHUAI, QI;DINGES, JURGEN |
分类号 |
C07C235/14;A61K31/4402;A61P3/10;C07C317/16;C07C323/41;C07D207/48;C07D213/64;C07D233/54;C07D257/04;C07D261/08 |
主分类号 |
C07C235/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|