发明名称 A METHOD OF PREDICTING OUTCOME IN CANCER PATIENTS
摘要 <p>A method of prognosis for a mammal with cancer is provided. The method includes the steps of determining in a biological sample obtained from the mammal the expression level of each biomarker of the group DSTN, TDRD3, RGS4, MYO1E, RPL3, Hypothetical FLJ13769, ANP32C, MC2R, DKFZp434L092, GPR27, HPS and LCP1; comparing the expression level of each biomarker with the expression level of a housekeeping gene; and rendering a prognosis for the mammal of a greater than 50% survival for an extended period of time when the expression level of DSTN, TDRD3, RGS4, MYO1E, RPL3(1), RPL3(2), RPL3(3), Hypothetical FLJ13769 and ANP32C is decreased in comparison to the expression of the housekeeping gene, and the expression level of MC2R, DKFZp434L092, GPR27, HPS5 and LCP1 is increased in comparison to the expression of the housekeeping gene.</p>
申请公布号 WO2013091113(A1) 申请公布日期 2013.06.27
申请号 WO2012CA50937 申请日期 2012.12.21
申请人 MCMASTER UNIVERSITY 发明人 HALLETT, ROBIN;HASSELL, JOHN;DVORKIN, ANNA;BANE, ANITA
分类号 C12Q1/68;C40B30/04;C40B40/06;G01N33/48;G01N33/53 主分类号 C12Q1/68
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