METHOD FOR SIMULATING FOCAL BRAIN INJURY

摘要

FIELD: medicine.SUBSTANCE: simulating a severe craniocerebral injury in rats with a gross persistent neurologic impairment is ensured by a single impact applied to the intact dura through a burr hole in the frontal-parietal-temporal region at an impact energy between 0.06 J to 0.09 J. Applying the exact-force impact enables quickly forming uniform groups of the above laboratory animals with the most similar focal brain substance injury.EFFECT: obtaining more reliable results in developing and evaluating the new methods of treating a severe craniocerebral injury in humans.