发明名称 |
SCREENING METHOD FOR ANTICANCER DRUGS |
摘要 |
Use of an animal model of spontaneous metastasis bearing a tumor derived from a cell line RM72 (Accession No. NITE BP-1110) allows simultaneous evaluation of tumorigenesis and spontaneous cancer metastasis. Use of a screening method using the animal model of spontaneous metastasis allows the obtainment of a substance having an anticancer activity and/or an anti-metastatic activity. Use of another screening method for selecting a substance that increases the expression of RECK in a cancer cell allows the obtainment of a substance that can serve as an active ingredient in an anticancer drug.
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申请公布号 |
US2013167255(A1) |
申请公布日期 |
2013.06.27 |
申请号 |
US201113812715 |
申请日期 |
2011.07.29 |
申请人 |
NODA MAKOTO;MURAI RYUYA;KITAYAMA HITOSHI;YOSHIDA YOKO;KYOTO UNIVERSITY |
发明人 |
NODA MAKOTO;MURAI RYUYA;KITAYAMA HITOSHI;YOSHIDA YOKO |
分类号 |
A61K49/00;G01N33/50 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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