OLOPATADINE FORMULATION FOR TOPICAL ADMINISTRATION

摘要

PROBLEM TO BE SOLVED: To provide topical formulations of olopatadine for treating allergic or inflammatory disorders of an eye and nose.

SOLUTION: A solution formulation contains about 0.17-0. 62% (w/v) olopatadine and polyvinylpyrrolidone or polystyrene sulfonic acid in an amount sufficient to enhance the physical stability of the solution. A solution composition is topically administrable to treat allergic or inflammatory disorders of the eye and nose, which contains 0.17-0. 62% (w/v) olopatadine and a polymeric physical stability-enhancing ingredient consisting essentially of polyvinylpyrrolidone or polystyrene sulfonic acid in an amount sufficient to enhance the physical stability of the solution.

COPYRIGHT: (C)2013,JPO&INPIT