发明名称 |
Compositions and methods including B lymphocyte cell line expressing membrane immunoglobulin different from secreted immunoglobulin |
摘要 |
Compositions and methods are disclosed herein for producing one or more immunoglobulins in an isolated B lymphocyte cell line. An isolated recombinant cell line includes an isolated B lymphocyte cell line capable of expressing at least one endogenous membrane immunoglobulin reactive to a first antigen and at least one exogenously incorporated nucleic acid encoding at least one secreted immunoglobulin reactive to a second antigen.
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申请公布号 |
US2013164277(A1) |
申请公布日期 |
2013.06.27 |
申请号 |
US201113374353 |
申请日期 |
2011.12.22 |
申请人 |
HYDE RODERICK A.;KINDSVOGEL WAYNE R.;ELWHA LLC, A LIMITED LIABILITY COMPANY OF THE STATE OF DELAWARE |
发明人 |
HYDE RODERICK A.;KINDSVOGEL WAYNE R. |
分类号 |
A61K35/12;A61K39/00;A61K39/395;A61P37/04;C12N5/16;G01N33/53 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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