发明名称 |
COMBINATION THERAPY WITH INTERFERON AND ANDROGRAPHOLIDES FOR MULTIPLE SCLEROSIS |
摘要 |
<p>The effectiveness of interferon for treating multiple sclerosis and other demyelinating diseases is synergistically potentiated by concomitant administration of a compound of Formula (I): wherein R1 is H, alkyl or OH, R2 is hydroxyalkyl or alkyl-O-L1, R3 is H or OH, X is C(=CH2), CH(OH), or spirooxirane-2, Z is CH2 CH(OH) or C(=0), and R4 is an optionally substituted L2-alkyl or L2-alkenyl, wherein L2 is an optionally substituted 3-furanyl or 3-fur-3-enyl moiety.</p> |
申请公布号 |
CA2853779(A1) |
申请公布日期 |
2013.06.27 |
申请号 |
CA20122853779 |
申请日期 |
2012.12.19 |
申请人 |
INNOBIOSCIENCE, LLC;HANCKE OROZCO, JUAN L.;BURGOS, RAFAEL |
发明人 |
HANCKE OROZCO, JUAN L.;BURGOS, RAFAEL |
分类号 |
A61K38/21;A61K31/365;A61P21/00;A61P25/28 |
主分类号 |
A61K38/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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