| 发明名称 |
COMPOUNDS AND METHODS FOR IMPROVING CELLULAR UPTAKE OF OLIGOMERIC COMPOUNDS |
| 摘要 |
The present invention provides method of optimizing the efficacy and potency of antisense drugs. In certain embodiments, the invention provides assays useful for determining favorable oligonucleotide characteristics and excipeints for improved cellular uptake.
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| 申请公布号 |
US2013164844(A1) |
申请公布日期 |
2013.06.27 |
| 申请号 |
US201213658544 |
申请日期 |
2012.10.23 |
| 申请人 |
ISIS PHARMACEUTICALS, INC.;ISIS PHARMACEUTICALS, INC. |
发明人 |
KOLLER ERICH;BENNETT C. FRANK |
| 分类号 |
C12Q1/02;C12N15/11 |
主分类号 |
C12Q1/02 |
| 代理机构 |
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