| 发明名称 |
BISAMINOETHANETHIOL-TARGETING LIGAND CONJUGATES AND COMPOSITIONS |
| 摘要 |
The invention provides, in a general sense, a new labeling strategy employing 99mTc chelated with ethylenedicysteine (EC). EC is conjugated with a variety of ligands and chelated to 99mTc for use as an imaging agent for tissue-specific diseases. The drug conjugates of the invention may also be used as a prognostic tool or as a tool to deliver therapeutics to specific sites within a mammalian body. Kits for use in tissue-specific disease imaging are also provided.
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| 申请公布号 |
US2013165631(A1) |
申请公布日期 |
2013.06.27 |
| 申请号 |
US201213552414 |
申请日期 |
2012.07.18 |
| 申请人 |
YANG DAVID J.;LIU CHUN W.;YU DONG-FANG;KIM E. EDMUND;BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
YANG DAVID J.;LIU CHUN W.;YU DONG-FANG;KIM E. EDMUND |
| 分类号 |
A61K51/04;C07D233/91;A61K51/00;A61K51/08;C07D233/92;C07D409/12;C07D475/04;C07D475/06;C07H23/00 |
主分类号 |
A61K51/04 |
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